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[Experience with clindamycin in stomatologic diseases].
1Magyar Honvédség Központi Honvédkórház, HIETE Oktató-Továbbképzó Kórház, Szájsebészeti és Fogászati Osztály, Budapest.
Fogorvosi Szemle
|August 27, 1999
Summary
Clindamycin effectively treated dental inflammatory diseases and post-surgical infections in 97% of patients. This antibiotic demonstrated a favorable safety profile, making it a viable option for stomatological conditions.
Area of Science:
- Dentistry
- Pharmacology
- Infectious Diseases
Background:
- Dental inflammatory diseases and post-surgical infections pose significant clinical challenges.
- Effective antibiotic therapy is crucial for managing these conditions and preventing complications.
Purpose of the Study:
- To evaluate the efficacy and safety of clindamycin in treating dental inflammatory diseases and in patients undergoing dental surgical procedures.
- To assess the clinical outcomes and side effects of a 7-day clindamycin regimen.
Main Methods:
- A Phase IV Good Clinical Practice (GCP) study involved 155 patients with dental inflammatory diseases or undergoing dental surgery.
- Patients received clindamycin at a dosage of 3 x 300 mg/day for 7 days.
Main Results:
- Clindamycin demonstrated high effectiveness, with 97% (150 out of 155) of patients showing positive treatment outcomes.
- A low incidence of mild side effects was observed in only 2 cases, indicating good tolerability.
Conclusions:
- Clindamycin is a highly effective and well-tolerated antibiotic for the treatment of various stomatological diseases.
- The findings support the recommendation of clindamycin for managing dental infections and in the perioperative setting for dental surgery.