The effects of electroconvulsive shock on retinal activity

Two experiments are reported examining the effects of electroconvulsive shock (ECS) on the electroretinogram (ERG) and the retinal oscillatory potentials (OPs) in the albino rat. Immediately after the induction of generalised seizure activity, both the ERG and the OPs were always preserved basically intact, despite minor alterations to their waveforms. In Experiment 1, it was found that small changes in amplitude of the ERG were recorded following ECS, but these were most likely artifactual. The only other notable finding was a temporary decrease in latency of the b-wave of the ERG. In Experiment 2, a slight overall attenuation in the amplitude of the OPs was observed. This was associated with a paradoxical decrease in the latencies of all three OP subcomponents similar to that found for the ERG b-wave. It is concluded that ECS does not interfere to any marked extent with either the transduction of the visual signal or its processing within the various retinal layers. This implies that the blockade of the afferent volley that occurs following ECS must be confined to the optic pathway or to the occipital cortex itself.