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Life-threatening tamoxifen-induced hypercalcaemia
P M Mulvenna1, A J Wright, T J Podd
1Northern Centre for Cancer Treatment, Newcastle General Hospital, Newcastle upon Tyne, UK.
Clinical Oncology (Royal College of Radiologists (Great Britain))
|August 28, 1999
Abstract:
This case report serves to emphasize two important features of metastatic breast carcinoma. First, that tamoxifen-induced flare, although a rare and self-limiting phenomenon, may be fatal and must thus be recognized and treated promptly. Secondly, those patients presenting with hypercalcaemia, as part of tamoxifen-induced tumour flare, invariably have metastatic disease but they may enjoy a durable prognosis if this is confined to the skeleton.