Exploiting the p53 pathway for cancer diagnosis and therapy

Simultaneous measurement of p53:Mdm2 and p53:Mdm4 protein-protein interactions in whole cells using fluorescence labelled foci.

Scientific reports·2019

Synthetic 10FN3-based mono- and bivalent inhibitors of MDM2/X function.

Protein engineering, design & selection : PEDS·2018

Enhancing Specific Disruption of Intracellular Protein Complexes by Hydrocarbon Stapled Peptides Using Lipid Based Delivery.

Scientific reports·2017

The hot-spot p53R172H mutant promotes formation of giant spermatogonia triggered by DNA damage.

Oncogene·2016

p53 isoforms regulate astrocyte-mediated neuroprotection and neurodegeneration.

Cell death and differentiation·2016

Tumor-specific signaling to p53 is mimicked by Mdm2 inactivation in zebrafish: insights from mdm2 and mdm4 mutant zebrafish.

Oncogene·2015

Role of orphan G protein-coupled receptor GPR52 in breast cancer cell multicellular organization and collective invasion.

British journal of cancer·2026

CD39+CD103+CD8+ T cells enhance neoadjuvant chemoimmunotherapy efficacy in head and neck squamous cell carcinoma.

British journal of cancer·2026

Kdm2a histone demethylase ablation restores anti-tumor immunogenicity in liver cancer.

British journal of cancer·2026

Mapping B7-H3 in the tumour microenvironment: a systematic review of stromal, vascular and immune expression.

British journal of cancer·2026

Risk of urologic cancers in patients with hospital-diagnosed recurrent cystitis: a nationwide population-based study.

British journal of cancer·2026

Paediatric therapeutic development workshop on osteosarcoma.

British journal of cancer·2026

Metastatic Urothelial Carcinoma of the Bladder to the Retina: A Clinicopathological Correlation and Review of the Literature.

Retina (Philadelphia, Pa.)·2026

Preoperative Diagnosis of the Bile Duct Traumatic Neuroma by Endoscopic Ultrasound-guided Tissue Acquisition: A Case Report.

DEN open·2026

Severe hypercalcemia in a patient with end-stage liver disease.

JCEM case reports·2026

Endoscopic submucosal dissection for a giant circumferential early rectal cancer with massive schistosoma egg deposition: a case report.

Frontiers in surgery·2026

UNC93B1 drives IL-6/STAT3-dependent tumor-macrophage crosstalk and epithelial-mesenchymal transition in breast cancer.

Frontiers in pharmacology·2026

Early esophageal squamous neoplasia and the microbiome: evidence, mechanisms, and early-detection potential.

Frontiers in microbiology·2026

Related Experiment Videos

Exploiting the p53 pathway for cancer diagnosis and therapy

Related Concept Videos

Simultaneous measurement of p53:Mdm2 and p53:Mdm4 protein-protein interactions in whole cells using fluorescence labelled foci.

Synthetic 10FN3-based mono- and bivalent inhibitors of MDM2/X function.

Enhancing Specific Disruption of Intracellular Protein Complexes by Hydrocarbon Stapled Peptides Using Lipid Based Delivery.

The hot-spot p53R172H mutant promotes formation of giant spermatogonia triggered by DNA damage.

p53 isoforms regulate astrocyte-mediated neuroprotection and neurodegeneration.

Tumor-specific signaling to p53 is mimicked by Mdm2 inactivation in zebrafish: insights from mdm2 and mdm4 mutant zebrafish.

Role of orphan G protein-coupled receptor GPR52 in breast cancer cell multicellular organization and collective invasion.

CD39+CD103+CD8+ T cells enhance neoadjuvant chemoimmunotherapy efficacy in head and neck squamous cell carcinoma.

Kdm2a histone demethylase ablation restores anti-tumor immunogenicity in liver cancer.

Mapping B7-H3 in the tumour microenvironment: a systematic review of stromal, vascular and immune expression.

Risk of urologic cancers in patients with hospital-diagnosed recurrent cystitis: a nationwide population-based study.

Paediatric therapeutic development workshop on osteosarcoma.

Metastatic Urothelial Carcinoma of the Bladder to the Retina: A Clinicopathological Correlation and Review of the Literature.

Preoperative Diagnosis of the Bile Duct Traumatic Neuroma by Endoscopic Ultrasound-guided Tissue Acquisition: A Case Report.

Severe hypercalcemia in a patient with end-stage liver disease.

Endoscopic submucosal dissection for a giant circumferential early rectal cancer with massive schistosoma egg deposition: a case report.

UNC93B1 drives IL-6/STAT3-dependent tumor-macrophage crosstalk and epithelial-mesenchymal transition in breast cancer.

Early esophageal squamous neoplasia and the microbiome: evidence, mechanisms, and early-detection potential.

Related Experiment Videos

Exploiting the p53 pathway for cancer diagnosis and therapy

Related Concept Videos

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