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Methylphenidate: increased abuse or appropriate use?
1Department of Psychiatry, Scott & White Hospital and Clinics, Temple, Tex., USA.
Journal of the American Pharmaceutical Association (Washington, D.C. : 1996)
|September 1, 1999
Summary
While media reports suggest widespread abuse of methylphenidate (MPD) for attention deficit hyperactivity disorder (ADHD), scientific literature lacks data to confirm this. Recommendations are provided to mitigate potential MPD abuse and diversion.
Area of Science:
- Pharmacology
- Neuroscience
- Public Health
Background:
- Growing concerns regarding increased methylphenidate (MPD) prescriptions for attention deficit hyperactivity disorder (ADHD).
- Need for evidence-based recommendations for healthcare providers managing ADHD patients.
Purpose of the Study:
- To investigate the extent of methylphenidate (MPD) abuse and diversion.
- To provide guidance for healthcare providers on the appropriate use of MPD in ADHD treatment.
Main Methods:
- Comprehensive literature search including Medline, Internet, and Paper Chase databases (1966-1998).
- Inclusion of case reports, review articles, news articles, and DEA publications on MPD.
- Analysis of available data on methylphenidate (MPD) abuse and diversion.
Main Results:
- Limited empirical data found to substantiate widespread claims of methylphenidate (MPD) abuse and diversion reported by media and DEA.
- Identified similarities in pharmacodynamics and pharmacokinetics between MPD and cocaine as a potential factor for abuse.
- Developed recommendations to minimize the risk of MPD abuse and diversion.
Conclusions:
- A balanced approach is necessary to weigh the therapeutic benefits of methylphenidate (MPD) against its abuse potential.
- Education for clinicians, patients, and families is crucial for the appropriate use of MPD in ADHD management.