Related Experiment Videos
Acute disseminated histoplasmosis complicated with hypercalcaemia
1Department of Internal Medicine, Chang Gung Memorial Hospital-Kaohsiung, Kaohsiung Hsien, Taiwan, Republic of China.
The Journal of Infection
|September 1, 1999
Summary
Acute disseminated histoplasmosis can cause hypercalcemia. Physicians should consider this fungal infection and immune deficiencies in patients with high calcium levels.
Area of Science:
- Mycology
- Immunology
- Endocrinology
Background:
- Histoplasmosis is a fungal infection caused by Histoplasma capsulatum.
- Disseminated histoplasmosis can affect multiple organs.
- Hypercalcemia is a potential complication of various conditions, including infections and immune disorders.
Observation:
- A case of acute progressive disseminated histoplasmosis complicated by hypercalcemia is presented.
- Literature review of similar cases was conducted.
Findings:
- Disseminated histoplasmosis can manifest with hypercalcemia.
- Impaired cellular-mediated immunity is often associated with this presentation.
Implications:
- Increased physician awareness of disseminated histoplasmosis as a cause of hypercalcemia is warranted.
- Consideration of underlying immune deficiencies is crucial in patients with unexplained hypercalcemia.
- Early diagnosis and treatment of histoplasmosis can prevent severe complications.