Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Panniculitis in juvenile dermatomyositis.

F E Ghali1, A M Reed, P A Groben

  • 1Department of Dermatology, University of North Carolina at Chapel Hill, USA.

Pediatric Dermatology
|September 1, 1999
PubMed
Summary

Panniculitis, inflammation of fat tissue, is a rare but clinically significant finding in dermatomyositis. Recognizing this association is crucial for diagnosing and managing juvenile dermatomyositis patients presenting with specific skin lesions.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Examining the Diagnostic Accuracy of a Novel Performance-Based Test for Alzheimer's Disease Screening.

The journal of prevention of Alzheimer's disease..·2024
Same author

Juvenile idiopathic arthritis and future risk for cardiovascular disease: a multicenter study.

Scandinavian journal of rheumatology·2016
Same author

Genome-wide association study identifies HLA 8.1 ancestral haplotype alleles as major genetic risk factors for myositis phenotypes.

Genes and immunity·2015
Same author

Use of atorvastatin in systemic lupus erythematosus in children and adolescents.

Arthritis and rheumatism·2011
Same author

Laboratory markers of cardiovascular risk in pediatric SLE: the APPLE baseline cohort.

Lupus·2010
Same author

Effect of chloroquine phosphate treatment on serum MMP-9 and TIMP-1 levels in patients with systemic lupus erythematosus.

Lupus·2010

Area of Science:

  • Dermatology
  • Rheumatology
  • Pathology

Background:

  • Juvenile dermatomyositis is an idiopathic inflammatory myopathy characterized by muscle inflammation and characteristic skin rashes.
  • Panniculitis, inflammation of subcutaneous fat, is an uncommon finding in dermatomyositis, often presenting subclinically.

Observation:

  • A 14-year-old boy with a 4-year history of dermatomyositis presented with tender, indurated plaques and nodules.
  • Histopathological examination revealed changes consistent with dermatomyositis and prominent lobular panniculitis without calcification.

Findings:

  • This case adds to the limited literature on clinical panniculitis associated with dermatomyositis, typically manifesting as indurated lesions on extremities and trunk.
  • While often a subclinical histopathological finding, panniculitis can be a clinically relevant feature in juvenile dermatomyositis.

Related Experiment Videos

Implications:

  • Highlights the importance of recognizing panniculitis as a potential clinical manifestation in juvenile dermatomyositis.
  • Suggests that clinicians should consider panniculitis in the differential diagnosis of subcutaneous lesions in patients with dermatomyositis.
  • Further research may elucidate the specific mechanisms linking dermatomyositis and panniculitis.