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Mannan binding lectin concentration and risk of miscarriage
D C Kilpatrick1, L Starrs, S Moore
1Academic Unit, Department of Transfusion Medicine, 2 Forrest Road, Edinburgh, EH1 2QN, and Gynaecology Clinic, The Royal Infirmary, Edinburgh, EH3 9YW, UK.
Recurrent miscarriage is associated with low concentrations of mannan-binding lectin (MBL), but it is not known below which value relative MBL deficiency becomes a significant risk factor. The sera of 397 patients (male and female) suffering from recurrent miscarriage and 376 controls were assayed for MBL and the data analysed. It was found that the lower the cut-off value, the greater the statistical strength of the association. It was concluded that only MBL concentrations
Recurrent miscarriage is associated with low concentrations of mannan-binding lectin (MBL), but it is not known below which value relative MBL deficiency becomes a significant risk factor. The sera of 397 patients (male and female) suffering from recurrent miscarriage and 376 controls were assayed for MBL and the data analysed. It was found that the lower the cut-off value, the greater the statistical strength of the association. It was concluded that only MBL concentrations
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