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Related Experiment Videos

Patient recruitment: US perspective.

P D Walson1

  • 1Division of Pharmacology/Toxicology, Children's Hospital, Columbus, Ohio 43205, USA.

Pediatrics
|September 2, 1999
PubMed
Summary
This summary is machine-generated.

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Recruiting children for drug trials presents significant challenges. This review examines common problems and suggests solutions for effective subject identification and enrollment in pediatric clinical research.

Area of Science:

  • Pediatric pharmacology
  • Clinical trial management
  • Bioethics

Background:

  • Conducting drug trials in pediatric populations faces numerous ethical, legal, economic, scientific, and practical hurdles.
  • Subject identification and enrollment, commonly known as recruitment, represent the most substantial obstacle in pediatric drug development.

Purpose of the Study:

  • To review the multifaceted challenges inherent in the pediatric drug trial recruitment process.
  • To propose actionable strategies and potential solutions for improving subject identification and enrollment in pediatric clinical trials.

Main Methods:

  • Literature review of existing challenges in pediatric clinical trial recruitment.
  • Analysis of ethical, legal, economic, and practical barriers to subject enrollment.
Keywords:
Biomedical and Behavioral Research

Related Experiment Videos

  • Synthesis of proposed solutions and best practices for recruitment.

    • Main Results:

    • Recruitment is identified as the primary difficulty in pediatric drug trials.
    • Various factors contribute to recruitment challenges, including parental consent, disease prevalence, and trial complexity.
    • Potential solutions involve community engagement, streamlined consent processes, and tailored recruitment approaches.

    Conclusions:

    • Addressing recruitment barriers is crucial for advancing pediatric drug development.
    • Implementing proposed solutions can enhance the efficiency and success rate of pediatric clinical trials.
    • Further research and collaboration are needed to optimize pediatric drug trial recruitment strategies.