Related Experiment Video
Updated: Jul 11, 2026
05:30
Controlled Cortical Impact Model for Traumatic Brain Injury
Published on: August 5, 2014
Summary
A human bite transmitted Group A Streptococcus, causing severe necrotizing fasciitis. Prompt medical intervention, including surgery and antibiotics, enabled complete leg healing without amputation.
Area of Science:
- Infectious Diseases
- Surgical Pathology
Background:
- Group A Streptococcus (GAS) is a significant human pathogen.
- Human bites can transmit various bacterial infections.
- Necrotizing fasciitis is a severe, rapidly progressing soft tissue infection.
Observation:
- A case of Group A Streptococcus transmission via a human bite is presented.
- The bite resulted in the development of severe necrotizing fasciitis in the affected limb.
Findings:
- Rapid surgical debridement and broad-spectrum antibiotic therapy were initiated.
- The patient received timely and aggressive medical management.
Implications:
- This case highlights the potential for GAS transmission through human bites.
- Prompt surgical and antibiotic treatment can effectively manage severe necrotizing fasciitis.
- Preservation of the infected limb is achievable with rapid intervention.
Related Concept Videos
01:22Burn Injuries
Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
01:29Blood and Nerve Supply to the Bones
Bones are dynamic organs that require a rich supply of oxygen and nutrients. Around 5% to 10% of the cardiac output supplies blood to the bones. A typical long bone has three main sources: the nutrient artery, the metaphyseal and epiphyseal arteries, and the periosteal arteries.
Nutrient Artery
The nutrient artery is the main blood vessel that enters the diaphysis via the nutrient foramen. While most long bones have only one nutrient foramen, large bones, such as the femur, may have two. This...
Nutrient Artery
The nutrient artery is the main blood vessel that enters the diaphysis via the nutrient foramen. While most long bones have only one nutrient foramen, large bones, such as the femur, may have two. This...
01:00Cellular Injury I: Introduction
Cellular injury occurs when a cell cannot maintain homeostasis or adapt to stressors such as hypoxia, toxins, or trauma. Depending on severity and duration, injury may be reversible, allowing recovery, or irreversible, leading to cell death.General Mechanisms of Cell InjuryAlthough causes vary, most cellular injuries arise from a few key mechanisms that disrupt essential functions and often amplify one another. Cell survival depends on the extent and balance of these disturbances.ATP depletion...
01:21Cellular Injury II: Classification
Cellular injury is any process that disrupts a cell’s ability to maintain homeostasis, leading to structural or functional changes. It is broadly classified based on etiology (cause) and mechanism of damage.Classification by EtiologyCellular injury may result from several causes. Hypoxic injury happens due to reduced oxygen delivery, most commonly from inadequate blood supply, such as arterial obstruction; for example, coronary artery thrombosis can cause myocardial infarction. Chemical injury...