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Laminitis as a systemic disease
1Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine, Texas A&M University, College Station, USA.
The Veterinary Clinics of North America. Equine Practice
|September 3, 1999
Summary
This study examines systemic effects in horses with laminitis, focusing on cardiovascular, renal, endocrine, and immunologic systems. It details nutritional and metabolic changes in chronic cases, discussing origins and clinical impacts.
Area of Science:
- Veterinary Medicine
- Equine Health
- Pathology
Background:
- Laminitis is a significant equine health concern.
- Systemic involvement in laminitis is complex and multifactorial.
- Understanding these systems is crucial for effective management.
Purpose of the Study:
- To present the clinical pathology of laminitis.
- To detail the involvement of cardiovascular, renal, endocrine, and immunologic systems.
- To discuss nutritional and metabolic alterations in chronically affected horses.
Main Methods:
- Review of available data on systemic involvement.
- Analysis of data concerning disease phase and severity.
- Discussion of origins and clinical implications of systemic findings.
Main Results:
- Laminitis involves significant cardiovascular, renal, endocrine, and immunologic system alterations.
- These systemic changes vary with disease phase and severity.
- Chronic laminitis is associated with distinct nutritional and metabolic disturbances.
Conclusions:
- Systemic pathology is integral to understanding laminitis.
- Clinical implications of these findings aid in diagnosis and treatment.
- Further research into systemic interactions can improve equine welfare.