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Related Experiment Videos

Relation between job strain and myocardial infarction: a case-control study.

B Netterstrøm1, F E Nielsen, T S Kristensen

  • 1Clinic of Occupational Medicine, Hillerød Hospital, Denmark. bone@fa.dk

Occupational and Environmental Medicine
|September 3, 1999
PubMed
Summary

High job strain, characterized by demanding work and low control, significantly increases myocardial infarction (MI) risk. Blue-collar jobs and private sector employment also elevate MI risk, confirming socioeconomic links.

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Area of Science:

  • Occupational health
  • Cardiovascular epidemiology
  • Psychosocial factors in health

Background:

  • Myocardial infarction (MI) is a leading cause of mortality globally.
  • Job-related factors and socioeconomic status are increasingly recognized as significant contributors to cardiovascular disease.
  • Karasek's job strain model provides a framework for understanding the impact of work environment on health.

Purpose of the Study:

  • To investigate the influence of job-related and socioeconomic factors on the development of myocardial infarction (MI).
  • To assess the applicability of Karasek's job strain and isostrain models to MI risk.
  • To identify specific occupational and socioeconomic variables associated with increased MI risk.

Main Methods:

  • A case-control study involving 76 male wage earners hospitalized with MI (cases) and 176 male wage earners without MI (controls).

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  • Data collected through extensive questionnaires on job-related conditions and psychosocial factors.
  • Analysis utilized Karasek's job strain model and its extension, the isostrain model.

    • Main Results:

    • High job strain (high demand, low control) was associated with a significantly increased odds ratio (OR) for MI (OR 2.1, 95% CI 1.2 to 3.8), even after adjustments.
    • Blue-collar job category (OR 2.8, 95% CI 1.6 to 5.8) and private sector employment (OR 3.1, 95% CI 1.8 to 6.1) showed significant associations with MI.
    • Adjustments for smoking, socioeconomic status, and social network did not substantially alter the OR for job strain.

    Conclusions:

    • The study validates Karasek's job strain model in relation to MI risk.
    • Confirms the established link between socioeconomic status and MI risk.
    • Highlights a novel finding of increased MI risk among private sector employees.