Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Another dissertation on poorly differentiated carcinomas: is it really necessary?

R H Nishiyama1

  • 1Maine Medical Center, Portland, USA.

Advances in Anatomic Pathology
|September 3, 1999
PubMed
Summary

This study refines the classification of poorly differentiated thyroid carcinomas, which have intermediate outcomes between well-differentiated and anaplastic types. The research aims to improve the identification of these challenging thyroid tumors in clinical practice.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Overview of surgical pathology of the thyroid gland.

World journal of surgery·2000
Same author

Polymerase chain reaction-based microsatellite polymorphism analysis of follicular and Hürthle cell neoplasms of the thyroid.

The Journal of clinical endocrinology and metabolism·1998
Same author

Nuclear DNA analysis of hyperplastic parathyroid glands in multiple endocrine neoplasia type I.

Archives of surgery (Chicago, Ill. : 1960)·1992
Same author

Single and multigland disease in primary hyperparathyroidism: clinical follow-up, histopathology, and flow cytometric DNA analysis.

World journal of surgery·1992
Same author

Primary hyperparathyroidism: pathology, flow cytometric DNA analysis, and surgical treatment.

Critical reviews in clinical laboratory sciences·1992
Same author

Effects of several commonly used fixatives on DNA and total nuclear protein analysis by flow cytometry.

American journal of clinical pathology·1989

Area of Science:

  • Endocrinology
  • Surgical Pathology
  • Oncology

Background:

  • Poorly differentiated thyroid carcinomas present intermediate prognoses between well-differentiated and anaplastic types.
  • These tumors are characterized by poorly differentiated areas within papillary and follicular carcinomas.
  • Sakamoto's classification identifies schirrous, solid, and trabecular areas for diagnosis, but similar areas can appear in less aggressive tumors, complicating identification.

Purpose of the Study:

  • To present a refined classification for poorly differentiated thyroid carcinomas.
  • To enhance the practical identification of these neoplasms in daily clinical practice.

Main Methods:

  • Review and refinement of Sakamoto's classification criteria for poorly differentiated thyroid carcinomas.

Related Experiment Videos

  • Histopathological analysis focusing on identifying specific architectural patterns within thyroid tumors.

    • Main Results:

    • The proposed refinement aims to improve the distinction of poorly differentiated thyroid carcinomas.
    • The classification acknowledges limitations similar to Sakamoto's original work but offers practical value.

    Conclusions:

    • A refined classification may aid in the more accurate diagnosis of poorly differentiated thyroid carcinomas.
    • Further validation is needed to confirm the practical utility and overcome existing diagnostic limitations.