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[Hematologic abnormalities and immunodepression in HIV/AIDS- related pulmonary tuberculosis]
A A Hane1, D Thiam, S Cissokho
1Clinique de pneumologie, CHU Fann, Dakar, Sénégal.
Bulletin De La Societe De Pathologie Exotique (1990)
|September 3, 1999
Abstract:
Our objectives were to describe hemato-immunological abnormalities encountered in tuberculosis patients HIV seropositive (TBVIH+, n = 67) or not (TBVIH-, n = 39) and in HIV asymptomatic patients (aSVIH+, n = 40). We found: a great reduction of mean value of RBC and Hb in TBVIH+ and TBVIH-; a reduction of mean value of leucocytes, total lymphocytes and CD4+ lymphocytes in TBVIH+ and aSVIH+; an inversion of [formula: see text] ratio, more important in TBVIH+ than in aSVIH+. HIV and tuberculosis association, HIV1 serotype and CD4 < 200/mm3 were found to promote significantly hemato-immunological abnormalities.