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Related Experiment Videos

Frequency doubling technology perimetry using a 24--2 stimulus presentation pattern.

C A Johnson1, G A Cioffi, E M Van Buskirk

  • 1Devers Eye Institute, Discoveries in Sight Research Laboratory, Legacy Health Systems, Portland, Oregon 97210, USA.

Optometry and Vision Science : Official Publication of the American Academy of Optometry
|September 3, 1999
PubMed
Summary

A custom 24-2 stimulus pattern for frequency doubling technology (FDT) perimetry shows improved detection of early glaucoma. This enhanced FDT perimetry offers better characterization of visual field loss but requires a longer testing time.

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Area of Science:

  • Ophthalmology
  • Visual electrophysiology

Background:

  • Glaucoma diagnosis relies on detecting progressive visual field loss.
  • Frequency Doubling Technology (FDT) perimetry is a screening tool for glaucoma.
  • Optimizing FDT perimetry parameters may improve early detection of glaucomatous damage.

Purpose of the Study:

  • To evaluate if smaller targets and a 24-2 stimulus pattern enhance FDT perimetry's ability to detect and characterize early glaucomatous visual field loss.
  • To compare a custom FDT perimetry protocol with a commercial version.

Main Methods:

  • One hundred normal subjects and 53 glaucoma suspects/patients were tested.
  • Evaluations included commercial FDT perimetry (17 larger stimuli) and custom FDT perimetry (54 smaller stimuli, 24-2 pattern).
  • Test-retest reliability and sensitivity variations were analyzed.

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Main Results:

  • The custom 24-2 FDT test demonstrated similar dynamic range and aging characteristics to the commercial version.
  • Both FDT tests showed age-related sensitivity reduction and comparable test-retest reliability.
  • The custom 24-2 FDT test detected a greater percentage of abnormalities in early glaucoma and high-risk suspects.

Conclusions:

  • Frequency Doubling Technology (FDT) perimetry can be adapted with smaller targets and a 24-2 pattern, similar to conventional automated perimetry.
  • The 24-2 stimulus pattern offers modestly higher sensitivity for detecting early glaucomatous loss and better pattern characterization.
  • The improved detection comes at the cost of approximately doubled testing time.