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Related Experiment Videos

Fatigue and psychiatric disorder: different or the same?

G van der Linden1, T Chalder, I Hickie

  • 1Department of Psychiatry, University of Stellenbosch, Tygerberg, South Africa.

Psychological Medicine
|September 3, 1999
PubMed
Summary

Pure fatigue is common but unstable in primary care. Most patients recover or develop psychiatric disorders within six months, with persistent fatigue being rare and not predicting psychiatric issues.

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Area of Science:

  • General Practice
  • Psychiatry
  • Epidemiology

Background:

  • Fatigue and psychiatric symptoms are prevalent in the community.
  • Their interconnectedness and long-term outcomes are not well-understood.

Purpose of the Study:

  • To investigate the association between fatigue and psychiatric disorders in primary care.
  • To determine if 'pure' fatigue predicts subsequent psychiatric disorder.

Main Methods:

  • 1177 patients were recruited from UK primary care.
  • Fatigue and psychiatric disorder were assessed at three time points using the 12-item General Health Questionnaire and the 11-item Fatigue Questionnaire.

Main Results:

  • Fatigue and psychiatric disorder scores were highly correlated (r ≈ 0.6) but did not change significantly over time.

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  • Non-co-morbid fatigue did not predict the development of psychiatric disorder, nor did non-co-morbid psychiatric disorder predict future fatigue.
  • Persistent, non-co-morbid fatigue (present at two or more time points) affected 2.5% of patients.

    • Conclusions:

    • A distinct 'pure' fatigue state exists but is generally unstable.
    • Most individuals with pure fatigue either recover or develop psychiatric disorders within six months.
    • Persistent fatigue is uncommon in primary care and does not appear to be a predictor of subsequent psychiatric disorder.