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Contractile and protractile coordination within an actin filament sliding on myosin molecules
H Honda1, K Hatori, Y Igarashi
1Department of BioEngineering, Nagaoka University of Technology, Japan.
Biophysical Chemistry
|September 4, 1999
Abstract:
An actin filament exhibits distortions longitudinally when it slides upon myosin molecules. We observed that the actin filament demonstrated contractile distortions at low ATP concentrations and protractile distortions at high concentrations. Temporal development of such distortions was identified, by tracing each of several speckled fluorescent markers attached to the actin filament. Close association of the sliding movement to the moving distortions of an actin filament suggests the presence of a unitary mechanism regulating the apparently two different modes of dynamic movement.