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MRI features of Balo's concentric sclerosis
1Department of Diagnostic Radiology, Chang Gung University, Kwei Shan, Tao Yuan, Taiwan, Republic of China.
The British Journal of Radiology
|September 4, 1999
Summary
Balo
Area of Science:
- Neurology
- Radiology
Background:
- Balo's concentric sclerosis (BCS) is a rare demyelinating disorder.
- MRI is crucial for diagnosing BCS and monitoring disease progression.
Observation:
- A 56-year-old woman presented with progressive hemiparesis.
- MRI revealed characteristic concentric and laminated lesions in the frontal and frontoparietal regions.
Findings:
- Post-contrast MRI demonstrated classic concentric and laminated patterns indicative of BCS.
- The patient showed significant clinical improvement and lesion regression following corticosteroid therapy.
- BCS lesions exhibited prolonged persistence with residual concentric patterns despite recovery.
Implications:
- BCS can follow a prolonged, benign clinical course.
- Synchronous demyelination may underlie the concentric enhancement patterns observed in BCS.
- MRI findings in BCS can persist long-term, even after clinical recovery.