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[Peripheral blood stem cell transplantation--practices of mobilization and harvest]
Y Sugio1, Y Tokunaga, A Nomura
1Faculty of Medicine, Kyushu University.
Rinsho Byori. the Japanese Journal of Clinical Pathology
|September 4, 1999
Abstract:
Recently, mobilized peripheral blood stem cells (PBSC) are increasingly used as an alternative to bone marrow for engrafting procedures. Chemotherapy followed by recombinant human granulocyte-colony stimulating factor (rhG-CSF) or rhG-CSF alone are the most commonly used PBSC mobilization schedules. Current timing of apheresis has now been yet decided on time by flowcytometric analysis of CD34 positivity of peripheral blood whole white cell count. Because apheresis procedure has been established quite well, PBSC harvest procedure becomes fast, safe and stable.