Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Variable response to intracavernous prostaglandin E1 testing for erectile dysfunction.

K Lehmann1, H John, G Kacl

  • 1Urologic Clinic, University of Basel, Kantonsspital, Switzerland.

Urology
|September 4, 1999
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Leaf trait modification in European beech trees in response to climatic and edaphic drought.

Plant biology (Stuttgart, Germany)·2021
Same author

From open simple to robotic-assisted simple prostatectomy (RASP) for large benign prostate hyperplasia: the time has come.

World journal of urology·2021
Same author

A case report of cholinesterase inhibitor poisoning: cholinesterase activities and analytical methods for diagnosis and clinical decision making.

Archives of toxicology·2020
Same author

[Acral necrosis as a complication of urosepsis].

Der Urologe. Ausg. A·2014
Same author

Cloning of Petunia hybrida chloroplast DNA sequences capable of autonomous replication in yeast.

Plant molecular biology·2013
Same author

Pre-prostatic tissue removed in robotic assisted lymph node dissection for prostate cancer contains lymph nodes.

Urology annals·2013
Same journal

"Editorial Comment on "Vaginal Estrogen Prescription is Associated with Reduced Rates of Serious Adverse Outcomes in Women of All Age Groups With Recurrent Urinary Tract Infection: An Epic Cosmos Database Analysis".

Urology·2026
Same journal

The True Oral History of Buccal Mucosal Grafts for Male Urethral Stricture Repair.

Urology·2026
Same journal

Preventing Postpartum Pelvic Floor Dysfunction: Clinical Evidence and Policy Gaps in U.S. Coverage of Pelvic Floor Muscle Therapy.

Urology·2026
Same journal

Editorial Comment on "Through the Eyes of the Applicant: A Qualitative Study of the Urology Residency Match".

Urology·2026
Same journal

Editorial Comment on "A Histopathologic Assessment of Prostate Ductal Anatomy in Relation to Micro-Ultrasound".

Urology·2026
Same journal

Same-Day Discharge Following Multiport Robot-Assisted Simple Prostatectomy: A Prospective Feasibility Study of Outcomes, Costs, and Post-Discharge Healthcare Utilization.

Urology·2026
See all related articles

Anxiety can affect initial erectile response tests. Repeating the intracavernous injection test (ICIT) with prostaglandin E1 significantly improves erectile function assessment, reducing false-positive diagnoses.

Area of Science:

  • Urology
  • Andrology
  • Diagnostic Imaging

Background:

  • Anxiety and apprehension can negatively impact the initial erectile response to vasoactive agents during intracavernous injection tests.
  • This initial response is crucial for color Doppler duplex sonography (CDS) evaluations, and a poor first response may lead to misdiagnosis of vascular insufficiency.

Purpose of the Study:

  • To evaluate the impact of repeated intracavernous injection tests (ICIT) on erectile response.
  • To determine if a second ICIT improves diagnostic accuracy compared to the first test, especially when combined with CDS.

Main Methods:

  • 168 patients with erectile dysfunction underwent a standardized ICIT using 10 microg prostaglandin E1.
  • The ICIT response was recorded on a four-point scale and repeated after 10 days, combined with CDS.

Related Experiment Videos

  • Clinical response was correlated with end-diastolic flow velocity.

    • Main Results:

    • A significant improvement in erectile response was observed in the second ICIT compared to the first (P <0.0001).
    • 45% of patients showed improved responses, with 62% achieving rigidity sufficient for intercourse on the second test versus 53% on the first.
    • 114 patients (68%) had consistent responses between tests.

    Conclusions:

    • The erectile response to prostaglandin E1 intracavernous injection significantly improves with a second test.
    • Caution is advised when interpreting CDS results after a single injection due to potential false-positive diagnoses of vascular insufficiency.