RNA repair as a novel approach to genetic therapy

Generation and characterization of aptamers targeting factor XIa.

Thrombosis research·2017

A kallikrein-targeting RNA aptamer inhibits the intrinsic pathway of coagulation and reduces bradykinin release.

Journal of thrombosis and haemostasis : JTH·2017

Inhibiting the intrinsic pathway of coagulation with a factor XII-targeting RNA aptamer.

Journal of thrombosis and haemostasis : JTH·2013

A high affinity, antidote-controllable prothrombin and thrombin-binding RNA aptamer inhibits thrombin generation and thrombin activity.

Journal of thrombosis and haemostasis : JTH·2012

Antidote control of aptamer therapeutics: the road to a safer class of drug agents.

Current pharmaceutical biotechnology·2012

Antidote-controlled platelet inhibition targeting von Willebrand factor with aptamers.

Oligonucleotides·2007

Culture media alter retinal organoid physiology promoting AAV transduction and retinal ganglion cell survival.

Gene therapy·2026

Optogenetic vision restoration: translational barriers and emerging therapeutic strategies.

Gene therapy·2026

Mapping the global trends and hotspots of research on gene therapy and hair cell regeneration for hearing loss: a comprehensive data-mining-based study.

Gene therapy·2026

An engineered helper plasmid generates differential E4orf6 and L4-22/33K gene expression increasing AAV vector production.

Gene therapy·2026

A gene therapy approach to prevent dilated intercellular space, a hallmark of gastroesophageal reflux disease.

Gene therapy·2026

Precision correction of the GJB2 c.235delC mutation by prime editing in vitro.

Gene therapy·2026

The RNA helicase domain of NAT10 promotes the biogenesis of hypomodified ribosomes to enhance cancer cell proliferation.

Nature communications·2026

Machine-Vision-Authenticated Hue-Programmable Bilayer Heterostructures for Anticounterfeiting.

ACS applied materials & interfaces·2026

Sub-stoichiometric 5-methoxyuridine modification enables tunable immune evasion and protein expression from synthetic mRNAs.

Molecular therapy. Nucleic acids·2026

MOF-regulated aggregation-induced electrochemiluminescence for machine learning-assisted aptasensing of cancer marker.

Talanta·2026

Size-dependent surface engineering of magnetic micro/nanorobots for synergistic chemo-magnetothermal cancer therapy.

Chemical communications (Cambridge, England)·2026

A rare case of giant congenital melanocytic nevus: its embryological and molecular basis.

Folia medica·2026

Related Experiment Videos

RNA repair as a novel approach to genetic therapy

Related Concept Videos

Generation and characterization of aptamers targeting factor XIa.

A kallikrein-targeting RNA aptamer inhibits the intrinsic pathway of coagulation and reduces bradykinin release.

Inhibiting the intrinsic pathway of coagulation with a factor XII-targeting RNA aptamer.

A high affinity, antidote-controllable prothrombin and thrombin-binding RNA aptamer inhibits thrombin generation and thrombin activity.

Antidote control of aptamer therapeutics: the road to a safer class of drug agents.

Antidote-controlled platelet inhibition targeting von Willebrand factor with aptamers.

Culture media alter retinal organoid physiology promoting AAV transduction and retinal ganglion cell survival.

Optogenetic vision restoration: translational barriers and emerging therapeutic strategies.

Mapping the global trends and hotspots of research on gene therapy and hair cell regeneration for hearing loss: a comprehensive data-mining-based study.

An engineered helper plasmid generates differential E4orf6 and L4-22/33K gene expression increasing AAV vector production.

A gene therapy approach to prevent dilated intercellular space, a hallmark of gastroesophageal reflux disease.

Precision correction of the GJB2 c.235delC mutation by prime editing in vitro.

The RNA helicase domain of NAT10 promotes the biogenesis of hypomodified ribosomes to enhance cancer cell proliferation.

Machine-Vision-Authenticated Hue-Programmable Bilayer Heterostructures for Anticounterfeiting.

Sub-stoichiometric 5-methoxyuridine modification enables tunable immune evasion and protein expression from synthetic mRNAs.

MOF-regulated aggregation-induced electrochemiluminescence for machine learning-assisted aptasensing of cancer marker.

Size-dependent surface engineering of magnetic micro/nanorobots for synergistic chemo-magnetothermal cancer therapy.

A rare case of giant congenital melanocytic nevus: its embryological and molecular basis.

Related Experiment Videos

RNA repair as a novel approach to genetic therapy

Related Concept Videos

Related Articles