Pseudophakic cystoid macular edema treated with high-dose intravenous methylprednisolone

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T Abe¹, S Hayasaka, Y Nagaki

¹Department of Ophthalmology, Toyama Medical and Pharmaceutical University, Japan.

Journal of Cataract and Refractive Surgery

|September 7, 1999

Abstract

Purpose:

To evaluate the efficacy of high-dose methylprednisolone in the treatment of pseudophakic cystoid macular edema (CME).

Setting:

University-affiliated hospital.

Methods:

Four patients with pseudophakic CME who reported decreased visual acuities were treated with oral prednisolone (20 mg daily for 5 days), oral acetazolamide (500 mg daily for 5 days), and topical dexamethasone 0.1% and diclofenac 0.1% (4 times a day for 14 days). The CME did not resolve. Next, they were treated with high-dose (1000 mg daily) intravenous methylprednisolone for 3 days.

Results:

In 3 of 4 eyes, the CME resolved and visual acuity improved.

Conclusion:

High-dose methylprednisolone may be effective in the treatment of pseudophakic CME.

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