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Transient diabetes insipidus in a dog with acromegaly
1Department of Small Animal Internal Medicine, Faculty of Veterinary Medicine, University of Giessen, Germany.
The Journal of Small Animal Practice
|September 7, 1999
Abstract:
A nine-year-old female beagle with acromegaly and extreme polyuria and polydipsia during dioestrus is described. It was demonstrated that polyuria was related to an inadequate rise of arginine-vasopressin (AVP) levels after water deprivation and stimulation with hypertonic saline. Administration of AVP did not lead to a significant increase in urine osmolality or reduction of urine volume. Clinical signs, except for bony changes, completely disappeared following ovariohysterectomy.