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A Pipeline to Characterize Structural Heart Defects in the Fetal Mouse
Published on: December 16, 2022
Sequential segmental approach to fetal congenital heart disease
1Department of Diagnostic Imaging, Hospital for Sick Children, Universtiy of Toronto, Ontario, Canada. shi-joon.yoo@sickkids.on.ca
Insights
This review details a six-view sequential segmental approach for diagnosing congenital heart disease during fetal sonography. This method aids in evaluating fetal heart anatomy and identifying potential abnormalities.
Area of Science:
- Medical Imaging
- Cardiology
- Prenatal Diagnosis
Background:
- The sequential segmental approach is standard for diagnosing congenital heart disease.
- Its application in fetal sonography requires standardized protocols.
- Accurate prenatal diagnosis of congenital heart disease is crucial for timely intervention.
Purpose of the Study:
- To describe a sequential segmental approach for fetal echocardiography.
- To outline six essential sonographic views for evaluating fetal heart anatomy.
- To establish a standard protocol for acquiring these views.
Main Methods:
- Utilized a sequential segmental approach during fetal sonography.
- Acquired six standardized sonographic views: transverse abdominal, four-chamber, left and right ventricular outflow tracts, three-vessel view, and aortic arch.
- Correlated abdominal situs with atrial arrangement and assessed atrioventricular and ventriculoarterial junctions.
Main Results:
- Demonstrated the utility of six basic sonographic views for sequential segmental analysis of the fetal heart.
- Showcased how abdominal organ arrangement provides clues to atrial arrangement.
- Highlighted the importance of outflow tract, three-vessel, and aortic arch views for diagnosing great artery abnormalities.
Conclusions:
- A standardized six-view sequential segmental approach is effective for fetal echocardiography.
- This method facilitates comprehensive evaluation of fetal heart structure and diagnosis of congenital heart disease.
- The described protocol aids in consistent and accurate prenatal assessment of cardiac anomalies.
Abstract:
The sequential segmental approach is now universally used in the diagnosis of congenital heart disease. Its utilization during fetal sonography has not been well described. In this review, we show how the fetal heart can be approached in a sequential segmental manner by using six basic sonographic views. The transverse view of the fetal upper abdomen is obtained to determine the arrangement of the abdominal organs, which, in most cases, provides the important clues to the determination of the atrial arrangement. The four-chamber view is obtained to evaluate the atrioventricular junctions. The views of the left and right ventricular outflow tracts are obtained to evaluate the ventriculoarterial junctions. The three-vessel view and the aortic arch view are obtained for the evaluation of the arrangement and size of the great arteries, which provides the additional clues to the diagnosis of the abnormalities involving the ventriculoarterial junctions and the great arteries. The standard protocol to acquire these six basic views is also introduced.
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