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Updated: Aug 17, 2026

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis
Published on: June 2, 2015
Thrombocytopenic thrombotic purpura: severe clinic with no CT, minor MRI, but a SPECT correlate
Y Baron1, T Bargemann, P Harten
1Radiologische Abteilung, Städtisches Krankenhaus Kiel, Germany. yvonne_baron@radiology.ucsf.edu
Abstract:
A 28-year-old woman with primarily therapy refractory TTP was followed neuroradiologically over 6 months. Despite pronounced neurological and neuropsychiatric symptoms including hemiparesis and aphasia she had unremarkable CT scans on two occasions. Three MRI exams showed no correlate for her neurological symptoms except a small petechial cortical hemorrhage in the right parietooccipital gyrus which may account for her TTP-related anxiety disorder. A cerebral HMPAO-SPECT showed long-standing right-sided hypoperfusion compatible with residual vasculature changes. The possible causes for the clinico-neuroradiological discrepancies are discussed in view of the literature.
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