Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Are all H. pylori "bad"?].

J Gisbert1, J Pajares

  • 1Servicio de Aparato Digestivo, Departamento de Medicina, Hospital Universitario de "La Princesa", Universidad Autónoma de Madrid, Madrid, España.

Revista Espanola De Enfermedades Digestivas
|September 8, 1999
PubMed
Summary

The debate on Helicobacter pylori eradication therapy continues, with arguments for universal treatment versus selective eradication based on strain pathogenicity and potential benefits. The optimal approach for managing H. pylori infection remains unresolved.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Effectiveness of empirical <i>Helicobacter pylori</i> eradication therapy with furazolidone in Russia: results from the European Registry on <i>Helicobacter pylori</i> Management (Hp-EuReg)].

Terapevticheskii arkhiv·2023
Same author

Potential of native Beauveria pseudobassiana strain for biological control of Pine Wood Nematode vector Monochamus galloprovincialis.

Journal of invertebrate pathology·2015
Same author

Systematic reviews of the clinical effectiveness and cost-effectiveness of proton pump inhibitors in acute upper gastrointestinal bleeding.

Health technology assessment (Winchester, England)·2007
Same author

Helicobacter pylori and gastric cancer.

Hepato-gastroenterology·2002
Same author

A beta-2-adrenergic receptor activates adenylate cyclase in human erythrocyte membranes at physiological calcium plasma concentrations.

Blood cells, molecules & diseases·2000
Same author

Helminth fauna of the Iberian lynx, Lynx pardinus.

Journal of helminthology·1998

Area of Science:

  • Gastroenterology
  • Microbiology
  • Infectious Diseases

Background:

  • Helicobacter pylori infection is widespread, raising questions about whether it constitutes a disease in all cases or only under specific circumstances.
  • The management of H. pylori infection involves a critical decision regarding the administration of eradication therapy to all infected individuals or only to select patients.

Purpose of the Study:

  • To review the arguments supporting both generalized and selective H. pylori eradication therapy.
  • To explore the implications of these differing therapeutic strategies.

Main Methods:

  • A review of existing literature and arguments for and against universal H. pylori eradication.
  • Analysis of the potential risks and benefits associated with H. pylori infection and its treatment.

Related Experiment Videos

Main Results:

  • Arguments for generalized eradication include the absence of a 'healthy' carrier state, risks of peptic ulcer, gastric cancer, and lymphoma, and reducing the infection reservoir.
  • Arguments against generalized eradication suggest H. pylori's long-term coexistence with humans, its pathogenicity in only a minority, potential benefits of some strains, risks of antibiotic therapy, and the emergence of vaccines.

Conclusions:

  • Strong arguments exist for both universal and selective H. pylori eradication strategies.
  • The dilemma of 'good' versus 'bad' H. pylori strains and the optimal therapeutic approach remains unresolved.