Adherence of albunex to an apical left ventricular thrombus

A previously unrecognized left ventricular thrombus developed a distinct echogenic rim after intravenous injection of albumin microbubbles despite no visible opacification of the left-sided chambers. Absence of visible left ventricular opacification suggests a low density of microbubbles crossing the pulmonary vasculature and a high affinity of the microbubbles for the thrombus or its endothelial surface. These findings support previous observations that albumin microbubbles demonstrate transient adherence to abnormal endothelium.