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Thoracoabdominal aortic aneurysm in Cogan's syndrome
J F Tseng1, R P Cambria, H T Aretz
1Division of Vascular Surgery, Department of Surgery, Massachusetts General Hospital, Boston, 02114, USA.
Journal of Vascular Surgery
|September 8, 1999
Summary
Cogan's syndrome, an autoimmune disorder, can affect blood vessels. This study highlights two cases of aortic aneurysms in patients with this condition, suggesting a link between Cogan's syndrome and vascular disease.
Area of Science:
- Rheumatology
- Ophthalmology
- Cardiology
Background:
- Cogan's syndrome is an autoimmune disorder characterized by interstitial keratitis and audiovestibular dysfunction.
- The etiology of Cogan's syndrome remains unknown, but emerging evidence suggests it may involve systemic vasculitis.
Observation:
- This report reviews the vascular manifestations associated with Cogan's syndrome.
- Two cases of thoracoabdominal aortic aneurysm in patients diagnosed with Cogan's syndrome are presented.
Findings:
- Cogan's syndrome, previously recognized for ocular and auditory symptoms, is increasingly implicated in systemic vasculitis.
- The presence of thoracoabdominal aortic aneurysms in these patients underscores the potential for severe vascular complications.
Implications:
- These findings suggest that patients with Cogan's syndrome may be at increased risk for aortic aneurysms.
- Further research into the vascular aspects of Cogan's syndrome is warranted to improve patient monitoring and treatment strategies.