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Mutans streptococci suppression by chlorhexidine gel in toddlers
1Department of Pedodontics, Lund University, Malmö, Sweden. svante twetman@odpedo.lu.se
American Journal of Dentistry
|September 9, 1999
Summary
Daily toothbrushing with chlorhexidine gel significantly reduced oral mutans streptococci in young children. This effect on dental caries prevention was notable at one month post-treatment.
Area of Science:
- Pediatric Dentistry
- Microbiology
- Preventive Dentistry
Background:
- Oral mutans streptococci are key pathogens in early childhood caries.
- Effective preventive strategies are crucial for maintaining pediatric oral health.
Purpose of the Study:
- To evaluate the efficacy of daily chlorhexidine gel toothbrushing in reducing oral mutans streptococci levels.
- To assess the impact of this intervention in healthy 1.5-year-old children.
Main Methods:
- A 14-day intervention using 1% chlorhexidine gel for twice-daily toothbrushing.
- Oral microbial sampling via a modified chair-side technique.
- Quantification of mutans streptococci colonization at baseline, 1 month, and 3 months post-intervention.
Main Results:
- A statistically significant reduction (P < 0.01) in mutans streptococci was observed at the 1-month follow-up.
- A non-significant reduction in mutans streptococci was noted at the 3-month follow-up compared to baseline.
Conclusions:
- Daily chlorhexidine gel toothbrushing is effective in reducing oral mutans streptococci in young children.
- The antimicrobial effect demonstrates potential for early caries prevention strategies.