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Related Experiment Videos

[Brain surface clear cell ependymoma: case report].

K Fujimoto1, H Ohnishi, N Koshimae

  • 1Department of Neurosurgery, Ishinkai Yao General Hospital, Japan.

No Shinkei Geka. Neurological Surgery
|September 9, 1999
PubMed
Summary
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This study describes a rare brain tumor, clear cell ependymoma, found on the brain surface in a young boy. Surgical removal was successful, providing insights into this unusual tumor type.

Area of Science:

  • Neuro-oncology
  • Pathology

Background:

  • Ependymomas are typically intraventricular tumors.
  • Clear cell ependymoma is a rare subtype with distinct histological features.

Observation:

  • A 13-year-old boy presented with sensory deficits due to a left fronto-parietal cystic, calcified brain mass.
  • The tumor was located on the brain surface, separate from the ventricular system.

Findings:

  • Histopathology revealed oligodendroglioma-like cells with clear cytoplasm, perivascular pseudorosettes, and glial fibrillary acidic protein (GFAP) positivity.
  • Electron microscopy showed microvilli, confirming features of clear cell ependymoma.
  • The cyst wall lacked a basal membrane but showed positivity for EMA and GFAP.

Implications:

Related Experiment Videos

  • This case expands the known locations for clear cell ependymoma.
  • Understanding the histogenesis of the associated cyst may offer new therapeutic targets.