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Effect of dietary taurine on endogenous hypercholesterolemia in rats fed on phenobarbital-containing diets
H Mochizuki1, J Takido, H Yokogoshi
1School of Food and Nutritional Sciences, University of Shizuoka, Japan.
Bioscience, Biotechnology, and Biochemistry
|September 9, 1999
Abstract:
The effect of dietary taurine on endogenous hypercholesterolemia induced by a phenobarbital-containing diet was investigated. Supplemented taurine did not affect the concentrations of serum cholesterol, but further potentiated the accumulation of hepatic cholesterol in the hypercholesterolemic state induced by phenobarbital. It is suggested that taurine might amplify the hepatic cholesterogenesis in phenobarbital-induced hypercholesterolemia.