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Laxifloranone, a new phloroglucinol derivative from Marila laxiflora
H R Bokesch1, A Groweiss, T C McKee
1Laboratory of Drug Discovery Research and Development, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute-Frederick Cancer Research and Development Center, Frederick, Maryland 21702-1201, USA.
Journal of Natural Products
|September 10, 1999
Abstract:
A new polyisoprenylated phloroglucinol derivative has been isolated from the twigs of Marila laxiflora and characterized on the basis of 1D and 2D NMR spectra. Laxifloranone (1) shows moderate inhibition of the cytopathic effects of in vitro HIV infection.