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Published on: June 14, 2017
14-3-3 proteins: eukaryotic regulatory proteins with many functions
C Finnie1, J Borch, D B Collinge
1Department of Plant Biology, The Royal Veterinary and Agricultural University, Copenhagen, Denmark.
Plant Molecular Biology
|September 10, 1999
Summary
Plant 14-3-3 proteins regulate vital physiological processes by binding to target proteins. This review synthesizes recent plant research on 14-3-3 proteins and their binding motifs.
Area of Science:
- Plant Biology
- Molecular Biology
- Biochemistry
Background:
- 14-3-3 proteins are crucial regulators of diverse eukaryotic physiological processes.
- In plants, they modulate key enzymes like plasma membrane H+-ATPase and nitrate reductase.
Purpose of the Study:
- To review recent findings in plant 14-3-3 protein research.
- To explore 14-3-3 binding motifs and suggest future research directions.
Main Methods:
- Literature review and synthesis of existing research.
- Analysis of known 14-3-3 binding motifs in plant targets.
Main Results:
- 14-3-3 proteins bind to phosphorylated motifs on target proteins, affecting their activity or localization.
- These proteins function as homo- or heterodimers, potentially bridging target proteins.
Conclusions:
- 14-3-3 proteins play a significant role in plant physiology through diverse regulatory mechanisms.
- Further research into plant 14-3-3 binding motifs is warranted to fully elucidate their functions.
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