Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Trisomy 18 in Kuwait.

K K Naguib¹, S A Al-Awadi, M A Moussa

¹Kuwait Medical Genetic Centre.

International Journal of Epidemiology

|September 10, 1999

Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Histopathological effects of azithromycin on broilers: immune system alterations and apoptotic changes.

British poultry science·2025

Same author

Prognostic significance of microRNA 17-92 cluster expression in Egyptian chronic lymphocytic leukemia patients.

Journal of the Egyptian National Cancer Institute·2021

Same author

Rapid evolution of our understanding of the pathogenesis of COVID-19: Implications for therapy.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde·2021

Same author

Have we learnt anything from COVID-19, and can we put it to good use in the future?

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde·2020

Same author

Paediatric inflammatory multisystem syndrome: What should we look out for in South Africa?

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde·2020

Same author

What are we doing to the children of South Africa under the guise of COVID-19 lockdown?

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde·2020

Trisomy 18 (Edwards

Area of Science:

Genetics
Pediatrics
Public Health

Background:

Trisomy 18 (Edwards' syndrome) is a common chromosomal abnormality.
This study describes 118 cases of Trisomy 18 in Kuwait from 1980-1997.

Purpose of the Study:

To investigate factors associated with Trisomy 18.
To determine the birth prevalence rate of Trisomy 18 in Kuwait.

Main Methods:

A case-control study comparing 118 Trisomy 18 cases with 131 healthy newborns.
Analysis included maternal and paternal age, birth order, abortion history, and malformations.
Multiple logistic regression was used to identify risk factors.

Main Results:

The female to male ratio was 2.1:1.

Keywords:

Age Factors Arab Countries Asia Case Control Studies Chromosome Abnormalities Demographic Factors Developing Countries Diseases Infant Kuwait Maternal Age Neonatal Diseases And Abnormalities Parental Age Paternal Age Population Population Characteristics Research Methodology Research Report Studies Western Asia Youth

Related Experiment Videos

Congenital heart and gastrointestinal anomalies were most common.

Maternal age over 30 was a significant risk factor (P=0.002).

The birth prevalence rate was 8.95 per 10,000 live births.

Conclusions:

Kuwait has a high birth prevalence of Trisomy 18.
Advanced maternal age is a significant risk factor for Trisomy 18.