Related Experiment Video

Updated: Oct 13, 2026

Surgical Models of Gastroesophageal Reflux with Mice
05:19

Surgical Models of Gastroesophageal Reflux with Mice

Published on: August 25, 2015

[Diagnosis and treatment of gastroesophageal reflux in children]

V G Bairov, V F Privorotskiĭ, Azizov BDzh

    Vestnik Khirurgii Imeni I. I. Grekova
    |September 11, 1999
    PubMed

    Insights

    This study analyzed 643 children with gastroesophageal reflux, detailing surgical outcomes. A novel surgical approach combining fundoplication and gastropexy showed no recurrences in 43 cases.

    Area of Science:

    • Pediatric Surgery
    • Gastroenterology

    Context:

    • Gastroesophageal reflux (GER) is a common condition in children.
    • Treatment strategies range from conservative management to surgical intervention.
    • Reflux-esophagitis can be associated with complications like esophageal stenosis.

    Purpose:

    • To analyze treatment outcomes for 643 children with gastroesophageal reflux.
    • To describe anesthetic methods and conservative treatment protocols.
    • To evaluate a novel surgical technique for refractory GER and associated conditions.

    Summary:

    • A retrospective analysis of 643 pediatric patients with GER was conducted.
    • Indications for surgery included hiatal hernias, cerebral palsy with reflux-esophagitis, and failed conservative treatment.
    • A combined fundoplication, posterior gastropexy, and esophageal fixation technique was employed in 43 patients with no recurrences.
    • Esophageal stenosis with Barrett's esophagus was managed with resection and reconstruction using colonic or local tissue grafts in 10 patients.

    Impact:

    • The proposed surgical method demonstrates promising results with no recurrence in the treated cohort.
    • Provides insights into surgical management of complex pediatric GER cases.
    • Highlights the importance of tailored surgical approaches for GER with complications.

    More Related Videos

    Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring06:46

    Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring

    Published on: December 14, 2020

    Construction of a Wireless-Enabled Endoscopically Implantable Sensor for pH Monitoring with Zero-Bias Schottky Diode-based Receiver08:25

    Construction of a Wireless-Enabled Endoscopically Implantable Sensor for pH Monitoring with Zero-Bias Schottky Diode-based Receiver

    Published on: August 27, 2021

    Related Concept Videos

    Gastroesophageal Reflux Disease I: Meaning and Pathophysiology01:29

    Gastroesophageal Reflux Disease I: Meaning and Pathophysiology

    Gastroesophageal Reflux Disease (GERD) involves the recurrent backflow of the stomach or duodenal contents into the esophagus, leading to troublesome symptoms and potential esophageal mucosal damage. Although GERD is often referred to as a disease, it is more accurately described as a syndrome, as it encompasses a range of symptoms and complications rather than a singular pathological entity, impacting a large number of individuals as the most prevalent upper gastrointestinal problem. Roughly...
    Gastroesophageal Reflux Disease II: Clinical Features and Management01:29

    Gastroesophageal Reflux Disease II: Clinical Features and Management

    Gastroesophageal reflux disease, or GERD, is a persistent medical condition that affects many individuals worldwide. Its clinical manifestations can vary greatly, making diagnosis and management challenging for healthcare professionals. The following is a comprehensive overview of the clinical manifestations, assessment, and management strategies for GERD.
    Clinical Manifestations
    GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
    Barrett Esophagus-II: Clinical Manifestations and Management01:21

    Barrett Esophagus-II: Clinical Manifestations and Management

    Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
    To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure entails...
    Esophageal Strictures-I: Introduction01:30

    Esophageal Strictures-I: Introduction

    Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
    Etiology
    The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
    Esophageal Strictures-II: Clinical Features and Management01:26

    Esophageal Strictures-II: Clinical Features and Management

    Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
    Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
    Gastroesophageal Reflux Disease01:25

    Gastroesophageal Reflux Disease

    Gastroesophageal reflux disease (GERD) is the backward flow of stomach contents (acid, pepsin, or bile) into the esophagus, causing mucosal inflammation known as esophagitis. It results from failure of antireflux mechanisms, mainly the lower esophageal sphincter (LES), influenced by mechanical and physiological factors.Etiology and Risk FactorsGERD develops when LES function is weakened or when intra-abdominal pressure increases. Risk factors include aging, obesity, and sliding hiatal hernia,...