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Effects of verapamil and CSL antivenom on Chironex fleckeri (box-jellyfish) induced mortality
D A Bloom1, J W Burnett, J R Hebel
1Department of Dermatology, School of Medicine, University of Maryland, Baltimore 21201, USA. jburnett@umaryland.edu
Toxicon : Official Journal of the International Society on Toxinology
|September 11, 1999
Abstract:
Ovine antivenom prolonged survival in mice challenged with intravenous Chironex fleckeri venom over a limited dose range. Verapamil enhanced the beneficial effect of ovine antivenom. This data suggests that there may be an, as yet undefined, optimal antivenom dose for humans and that verapamil, used in combination with antivenom is an effective agent.