Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Painless (silent) thyroiditis].

Y Ozawa1

  • 1Department of Endocrinology and Metabolism, Toranomon Hospital.

Nihon Rinsho. Japanese Journal of Clinical Medicine
|September 14, 1999
PubMed
Summary
This summary is machine-generated.

Silent thyroiditis (ST) is a common cause of thyrotoxicosis, often recurring in patients. Differentiating ST from Graves' disease (GD) is crucial due to overlapping symptoms and potential disease progression, highlighting the need for simpler diagnostic tests.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Bronchovascular cuff formation and lung lymph flow in edema formation of anesthetized sheep.

Lymphology·2009
Same author

The purinergic receptor P2Y, G-protein coupled, 2 (P2RY2) gene associated with essential hypertension in Japanese men.

Journal of human hypertension·2009
Same author

Diagnostic accuracy of 18F-2-deoxy-fluoro-D-glucose positron emission tomography for pN1 lymph nodes in patients with lung cancer.

Acta radiologica (Stockholm, Sweden : 1987)·2009
Same author

PLAP-1/asporin inhibits activation of BMP receptor via its leucine-rich repeat motif.

Biochemical and biophysical research communications·2008
Same author

Methotrexate-related lymphomatoid granulomatosis: a case report of spontaneous regression of large tumours in multiple organs after cessation of methotrexate therapy in rheumatoid arthritis.

Scandinavian journal of rheumatology·2007
Same author

New method for evaluation of lung lymph flow rate with intact lymphatics in anaesthetized sheep.

Acta physiologica (Oxford, England)·2006

Area of Science:

  • Endocrinology
  • Immunology

Context:

  • Silent thyroiditis (ST) is the second leading cause of thyrotoxicosis in Japan, after Graves' disease (GD).
  • Thyrotoxicosis pathogenesis differs: GD involves TSH receptor stimulation by antibodies, while ST likely results from autoimmune follicular destruction.
  • Distinguishing ST from GD typically relies on TSH receptor antibody titers and radioactive iodine uptake tests.

Purpose:

  • To highlight the diagnostic challenges in differentiating silent thyroiditis from Graves' disease.
  • To underscore the importance of accurate differential diagnosis due to disease recurrence and potential progression between conditions.
  • To emphasize the clinical need for a simpler diagnostic test specific to silent thyroiditis.

Summary:

  • Long-term observation revealed a high recurrence rate (65%) of silent thyroiditis.

Related Experiment Videos

  • Some patients experienced ST developing after GD, or GD developing after ST, complicating diagnosis.
  • The study indicates the critical need for improved diagnostic methods for silent thyroiditis, especially given its recurrence and relationship with Graves' disease.

    • Impact:

    • Improved diagnostic accuracy for thyrotoxicosis, particularly differentiating ST and GD.
    • Potential development of novel, simpler diagnostic tools for silent thyroiditis.
    • Enhanced patient management strategies for individuals with recurrent or overlapping thyroid disorders.