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Monitoring of antimicrobial therapy by an integrated computer program.

S Grau1, J Monterde, A Carmona

  • 1Department of Pharmacy, Hospital Universitari del Mar, Barcelona, Spain. 90126@imas.imim.es

Pharmacy World & Science : PWS
|September 14, 1999
PubMed
Summary
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A hospital computer program improved antimicrobial therapy monitoring, leading to significant cost savings and better patient outcomes. This tool enhances clinical pharmacist interventions and cost-effectiveness in antibiotic use.

Area of Science:

  • Pharmacoeconomics
  • Clinical Pharmacy
  • Health Informatics

Background:

  • Antimicrobial therapy requires careful monitoring to ensure efficacy and manage costs.
  • Hospital pharmacy departments play a crucial role in optimizing antibiotic use.
  • Information systems can support clinical decision-making in antimicrobial stewardship.

Purpose of the Study:

  • To evaluate a hospital-developed computer program for antimicrobial therapy monitoring.
  • To assess the program's impact on pharmaceutical costs and clinical outcomes.

Main Methods:

  • The computer application integrated data from Pharmacy and Microbiology departments.
  • It identified patients on controlled antibiotics for pharmacist review.
  • Pharmacists intervened on treatments, and the economic impact was quantified.

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Main Results:

  • 12.5% of monitored antibiotic treatments led to pharmaceutical interventions, with 92% acceptance.
  • Interventions frequently involved dosage/route adjustments for respiratory and urinary infections.
  • Accepted interventions yielded average annual savings of 83,359 USD.

Conclusions:

  • The computer program is a valuable tool for clinical pharmacists.
  • It facilitates more appropriate antibiotic therapeutics and improves cost-effectiveness.
  • The system contributes to achieving favorable clinical outcomes.