Related Experiment Videos
Interleukin-11: its biology and prospects for clinical use
J L Grosfeld1, X Du, D A Williams
1Department of Surgery, Indiana University School of Medicine, James Whitcomb Riley Hospital for Children, Indianapolis, USA.
JPEN. Journal of Parenteral and Enteral Nutrition
|September 14, 1999
Abstract:
IL-11 is a multifunctional cytokine that has pleiotropic effects on a variety of tissue including the bone marrow and intestinal mucosa. IL-11 is useful in elevating the platelet count in cancer patients with chemotherapy-induced thrombocytopenia and has a cytoprotective effect on the bowel mucosa in a variety of causes of gut damage and a trophic effect on the villi after massive bowel resection.