Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Negative interstitial pressure in the peritendinous region during exercise.

H Langberg1, D Skovgaard, J Bülow

  • 1Sports Medicine Research Unit, Department of Rheumatology H, Bispebjerg Hospital, DK-2400 Copenhagen, Denmark. HL02@bbh.hops.dk

Journal of Applied Physiology (Bethesda, Md. : 1985)
|September 14, 1999
PubMed
Summary

Human Achilles tendon exercise generates significant negative tissue pressure in the peritendinous space. This finding suggests a potential mechanism for exercise-induced fluid shifts and increased blood flow in the tendon region.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A vicious circle in chronic lymphoedema pathophysiology? An adipocentric view.

Obesity reviews : an official journal of the International Association for the Study of Obesity·2017
Same author

Applicability of contrast-enhanced ultrasound in the diagnosis of plantar fasciitis.

Scandinavian journal of medicine & science in sports·2017
Same author

The blunted effect of glucose-dependent insulinotropic polypeptide in subcutaneous abdominal adipose tissue in obese subjects is partly reversed by weight loss.

Nutrition & diabetes·2016
Same author

Danish VISA-A questionnaire with validation and reliability testing for Danish-speaking Achilles tendinopathy patients.

Scandinavian journal of medicine & science in sports·2015
Same author

In vivo biological response to extracorporeal shockwave therapy in human tendinopathy.

European cells & materials·2015
Same author

Equivalence of online and clinician administration of a patellar tendinopathy risk factor and severity questionnaire.

Scandinavian journal of medicine & science in sports·2014

Area of Science:

  • Physiology
  • Biomechanics
  • Sports Medicine

Background:

  • The Achilles tendon is crucial for locomotion.
  • Understanding peritendinous tissue pressure during exercise is vital for tendon health.
  • Previous studies noted increased blood flow during exercise, but the underlying mechanism was unclear.

Purpose of the Study:

  • To quantify tissue pressure in the peritendinous area of the human Achilles tendon during rest and exercise.
  • To investigate the effect of varying exercise intensity (torque) on this pressure.
  • To explore the role of negative tissue pressure in exercise-induced fluid dynamics.

Main Methods:

  • Tissue pressure measurements were taken in healthy individuals at rest and during isometric calf exercise at different torques.

Related Experiment Videos

  • Microdialysis with a colloid osmotic agent (Dextran 70) was employed to assess fluid shifts.
  • Measurements were performed at multiple locations proximal to the Achilles tendon insertion.

    • Main Results:

    • A significant, linear decrease in tissue pressure was observed with increasing exercise torque.
    • Negative tissue pressures were consistently generated during exercise, reaching substantial levels.
    • Dialysate volume was fully restored during exercise, indicating fluid shifts were counteracted.

    Conclusions:

    • Exercise generates marked negative tissue pressure in the Achilles tendon's peritendinous space.
    • This negative pressure may drive fluid shifts into the peritendinous tissue.
    • The findings support the hypothesis that negative tissue pressure contributes to exercise-induced hyperemia in the Achilles tendon.