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Investigation of children with chronic diarrhoea
B D Gupta1, S Bhaskar, A Karkra
1Department of Paediatrics, Regional Institute of Maternal and Child Health, Umaid Hospital, Dr. S.N Medical College, Jodhpur, India.
Insights
Lower gastrointestinal (G.I.) endoscopy and biopsy are crucial for diagnosing chronic diarrhea in children. This study highlights colitis as a common finding, emphasizing the need for both diagnostic methods.
Area of Science:
- Pediatric Gastroenterology
- Gastrointestinal Endoscopy
- Histopathology
Background:
- Chronic diarrhea in children poses diagnostic challenges.
- Accurate diagnosis is essential for effective management and improved outcomes.
Purpose of the Study:
- To investigate the utility of lower G.I. endoscopic and histopathological findings in pediatric chronic diarrhea.
- To determine the diagnostic yield of these procedures in identifying the causes of chronic diarrhea in children.
Main Methods:
- A prospective, hospital-based study was conducted.
- 83 children (33 with chronic diarrhea, 50 controls) up to 14 years were analyzed.
- Lower G.I. endoscopy and rectal biopsies were performed for histopathological examination.
Main Results:
- The majority of children (90.8%) were in the 0-5 year age group.
- A definitive diagnosis was achieved in 13% of children with chronic diarrhea.
- Colitis emerged as the most frequent diagnosis.
Conclusions:
- Endoscopic evaluation combined with histopathological analysis of biopsies is essential for diagnosing chronic diarrhea in children.
- These integrated diagnostic approaches improve the accuracy of diagnosis and guide appropriate treatment strategies.
Objective:
To study the lower G.I. endoscopic and histopathological findings in children with chronic diarrhoea.
Design:
Prospective analysis.
Setting:
Hospital based.
Subject:
83 children with age up to 14 years admitted in Umaid Hospital, Jodhpur including 33 subjects with chronic diarrhoea and 50 normal children in control group.
Methods:
All 83 children including study (33) and control group (50) underwent lower G.I. Endoscopy using FUJINON-SIG-ET sigmoidoscope in older children and PENTAX FG-23H gastroscope in younger children after proper preparation. Rectal biopsies were taken in all the subjects except one and was sent for histopathological examination.
Results:
Majority (90.8%) were in 0-5 year age group with median age of 3.8 years. We could finally reach to definitive diagnosis in 13% patients with chronic diarrhoea. Over all, colitis was the most common cause.
Conclusion:
Both, endoscopy and biopsy are needed to reach final diagnosis.