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Post-functional endoscopic sinus surgery methicillin-resistant Staphylococcus aureus sinusitis.

R S Jiang1, J W Jang, C Y Hsu

  • 1Department of Otolaryngology, Taichung Veterans General Hospital, Taiwan, Republic of China.

American Journal of Rhinology
|September 15, 1999
PubMed
Summary
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Methicillin-resistant Staphylococcus aureus (MRSA) can cause difficult-to-treat infections after functional endoscopic sinus surgery (FESS). Quinolone antibiotics showed a 76.5% improvement rate in these post-FESS MRSA infections.

Area of Science:

  • Infectious Diseases
  • Otolaryngology
  • Bacteriology

Background:

  • Methicillin-resistant Staphylococcus aureus (MRSA) is a virulent pathogen causing nosocomial and sporadic infections.
  • Chronic sinusitis is a condition often treated with functional endoscopic sinus surgery (FESS).

Purpose of the Study:

  • To investigate the incidence and outcomes of postoperative MRSA infections in patients undergoing FESS.
  • To evaluate the effectiveness of antibiotic treatment, specifically quinolones, for these infections.

Main Methods:

  • Retrospective analysis of 358 chronic sinusitis patients who underwent FESS between July 1995 and June 1997.
  • Identification and clinical data collection for patients who developed postoperative MRSA infections.
  • Assessment of treatment strategies and patient outcomes, focusing on quinolone antibiotic efficacy.

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Main Results:

  • Eighteen out of 358 patients (5%) developed postoperative MRSA infections.
  • Most infected patients presented with mucopurulent nasal discharge and/or nasal crust.
  • Treatment with quinolone antibiotics resulted in a 76.5% improvement rate among the 17 evaluable patients.

Conclusions:

  • MRSA infections represent a significant postoperative complication following FESS.
  • These infections can complicate patient recovery and potentially impact the overall outcome of FESS.
  • Quinolone antibiotics offer a viable treatment option with a notable improvement rate for post-FESS MRSA infections.