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Related Experiment Videos

Ocular physiology and artificial tears.

A López-Alemany1, R Montés-Micó, M García-Valldecabres

  • 1Departament d'Optica, Facultat de Física, Universitat de València, Spain.

Journal of the American Optometric Association
|September 15, 1999
PubMed
Summary
This summary is machine-generated.

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Artificial tears solutions generally maintain a stable pH within the ocular comfort range, showing no significant changes over 60 days. This stability ensures they are safe for ocular physiology and contact lens wear.

Area of Science:

  • Ophthalmology
  • Optometry
  • Biomedical Engineering

Background:

  • Artificial tears are formulated to match the ocular comfort range and physiological tear pH.
  • Evaluating the pH stability of artificial tears is crucial for ocular health.

Purpose of the Study:

  • To assess the pH stability of nine artificial tears solutions over a 60-day period.
  • To determine if artificial tears' pH remains within the ocular comfort range over time.

Main Methods:

  • Randomly selected 15 bottles from different production lots for each of the nine artificial tears solutions.
  • Measured pH daily using a micropH 2002 Crison pH-meter over 60 days, with daily 0.05 ml increments.

Main Results:

  • All tested artificial tears solutions maintained pH values within the ocular comfort range.

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  • No statistically significant pH variations were observed over the 60-day study period (p > 0.01).
  • Significant differences in pH were noted between various artificial tears solutions, with some closer to physiological tear pH than others.

    • Conclusions:

    • The evaluated artificial tears solutions are unlikely to negatively impact ocular physiology or contact lens wear.
    • Healthcare practitioners should be aware of individual artificial tears solution properties to select appropriate options for patients.