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[Cerebral deep vein thrombosis: three cases].
C Di Roio1, C Jourdan, H Yilmaz
1Département d'Anesthésie-Réanimation, Hôpital neurologique et neurochirurgical Pierre Wertheimer, Lyon.
Revue Neurologique
|September 16, 1999
Summary
Cerebral venous sinus thrombosis is a rare condition in adult males, often presenting with severe neurological symptoms. Despite intensive care, all reported cases were fatal, highlighting diagnostic and therapeutic challenges.
Area of Science:
- Neurology
- Vascular Medicine
Background:
- Cerebral venous sinus thrombosis (CVST) is an uncommon cause of stroke.
- Diagnosis can be challenging, particularly in non-traditional presentations.
Observation:
- Three adult male cases of cerebral internal venous thrombosis are presented.
- Clinical manifestations included headaches, vomiting, dizziness, coma, intracranial hypertension, and cardiocirculatory arrest.
- Diagnostic imaging (CT scan, cerebral angiography) confirmed thrombosis, revealing hemorrhagic/ischemic lesions, cerebral edema, and hydrocephalus.
Findings:
- No patient survived despite comprehensive intensive care, including anticoagulation, CSF drainage, osmotherapy, and mechanical ventilation.
- Pre-existing conditions like sickle cell disease, radiotherapy for pineal tumors, or suspected autoimmune disease were noted in two and three cases, respectively.
- The rarity and diagnostic difficulty of CVST are emphasized.
Implications:
- This case series underscores the poor prognosis of cerebral internal venous thrombosis.
- It highlights the need for increased awareness and timely diagnosis of CVST.
- Further research into optimal treatment strategies for this rare condition is warranted.