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Asymmetric synthesis of some substituted-3-phenyl prolines
F Micheli1, R Di Fabio, C Marchioro
1Glaxo Wellcome S.p.A., Medicines Research Centre, Verona, Italy. fm20244@glaxowellcome.co.uk
Abstract:
The asymmetric synthesis of carboxyphenyl prolines was performed according to Schöllkopf methodology, to prepare possible antagonists of the metabotropic glutamate receptor mGluR1.