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Updated: Oct 19, 2026

A Model of Reverse Vascular Remodeling in Pulmonary Hypertension Due to Left Heart Disease by Aortic Debanding in Rats
Published on: March 1, 2022
Oxygen-dependent chronic obstructive pulmonary disease does not prohibit aortic aneurysm repair
M K Eskandari1, R Y Rhee, D L Steed
1Division of Vascular Surgery, University of Pittsburgh Medical Center, Pennsylvania, USA.
Background:
Severe oxygen-dependent chronic obstructive pulmonary disease (COPD) is considered by many to be a contraindication to open abdominal aortic aneurysm (AAA) repair. We reviewed our own experience with this patient population.
Methods:
From July 1995 to March 1999, 14 consecutive patients limited by home oxygen-dependent COPD underwent elective open infrarenal AAA repair. Their medical records were reviewed.
Results:
The mean aortic aneurysm size was 6.3 cm. The mean PaO2 = 70 mm Hg, PaCO2 = 45 mm Hg, forced expiratory volume in 1 second (FEV1) = 34% of predicted, and forced vital capacity (FVC) = 67% of predicted. All 14 patients were extubated within 24 hours, mean length of hospital stay was 5.9 days, and there were no perioperative deaths.
Conclusions:
Severe home oxygen-dependent COPD is not a contraindication to safe elective open AAA repair.
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