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Risk factors for pediatric presumed microbial keratitis: a case-control study
1Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi. rbvajpay@medinst.ernet.in
Cornea
|September 16, 1999
Summary
Pediatric microbial keratitis in India is linked to poverty, with corneal trauma and systemic illness as common causes. Staphylococcus species were the most frequent bacterial isolates.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Pediatrics
Background:
- Microbial keratitis is a significant cause of corneal opacity and vision loss in children.
- Understanding risk factors and clinical characteristics is crucial for effective management of pediatric microbial keratitis.
Purpose of the Study:
- To identify risk factors for pediatric presumed microbial keratitis.
- To describe the clinical presentation, microbiology, treatment, and outcomes of pediatric microbial keratitis.
Main Methods:
- A case-control study compared 50 children (≤12 years) with corneal ulceration to 50 controls.
- Evaluated risk factors including immunization, nutrition, and socioeconomic status.
- Clinical data, microbiology, treatment, and 3-month visual outcomes were analyzed.
Main Results:
- Lower socioeconomic status was significantly associated with corneal ulceration.
- Corneal trauma (38%) and systemic illness (24%) were primary predisposing factors.
- Staphylococcus species (70%) were the most common isolates; 22% achieved 6/18 or better vision at 3 months.
Conclusions:
- Pediatric corneal ulceration in India is associated with poverty.
- Early diagnosis and treatment are essential to improve visual outcomes in affected children.