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Related Experiment Videos

Complete genomes in WWW Entrez: data representation and analysis.

T A Tatusova1, I Karsch-Mizrachi, J A Ostell

  • 1National Center for Biotechnology Information (NCBI), National Library of Medicine, National Institutes of Health, Bethesda, MD 208944, USA. tatiana@ncbi.nlm.nih.gov

Bioinformatics (Oxford, England)
|September 17, 1999
PubMed
Summary

The National Center for Biotechnology Information (NCBI) Entrez system now offers improved access to complete viral, bacterial, and yeast genomes. Scientists can explore these genomic datasets with new web-based views and analytical tools for deeper biological insights.

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Area of Science:

  • Bioinformatics
  • Genomics
  • Computational Biology

Background:

  • Vast amounts of genome sequence data are publicly available.
  • The National Center for Biotechnology Information (NCBI) Entrez system provides access to this data.
  • Traditional data access methods are limited in scope.

Purpose of the Study:

  • To report recent improvements to the Entrez Genomes system.
  • To enhance the exploration of completely sequenced genomes.
  • To provide scientists with better access to genomic data insights.

Main Methods:

  • Utilizing the NCBI Entrez search and retrieval system.
  • Implementing flexible web-based views for genomic data.
  • Integrating precomputed relationships and analytical tools.

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Main Results:

  • Improvements have been made to access completely sequenced genomes (viruses, bacteria, yeast).
  • New features include flexible web-based views and precomputed relationships.
  • Immediate access to analytical tools is now available.

Conclusions:

  • The enhanced Entrez Genomes system offers a portal for exploring completed genome sequences.
  • Scientists can gain new insights from viral, bacterial, and yeast genomes.
  • Improved data accessibility facilitates genomic research.