Color Doppler sonography in the detection of parathyroid adenomas

Various diagnostic modalities have been utilized to aid in the detection of abnormal parathyroid tissue; however, its localization is not always easy. The purpose of this study was to determine whether the evaluation of potential hemodynamic changes in thyroid arteries could aid in the detection of parathyroid adenomas.

Twenty-eight patients with laboratory evidence of hyperparathyroidism were examined with color Doppler sonography. Data were collected for the superior and inferior thyroid arteries separately. These findings were compared with data for a control group of 14 healthy subjects.

Retrospective analysis of the data indicated that peak systolic velocities in the inferior thyroid arteries ipsilateral with the parathyroid adenomas were significantly higher than in normal controls (p <.001). Peak velocity values in the superior thyroid arteries ipsilateral with parathyroid adenomas located in the upper position were also significantly increased compared with those in control subjects (p <. 02). Conversely, peak velocities in the inferior and superior thyroid arteries contralateral with the adenomas, as well as velocities in the superior thyroid arteries ipsilateral with lower position adenomas, did not differ significantly from those in control subjects. The localization of both side and level site of the adenomas presented an accuracy of 86.6%, sensitivity reached 96. 5%, and specificity 83.1%.

Our results suggest that color Doppler sonography can be used to improve diagnostic accuracy in detecting parathyroid adenomas.