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Mitochondria in the life and death of neurons
1CNS Research Institute, Brigham & Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Essays in Biochemistry
|September 17, 1999
Abstract:
A prolonged decrease in ATP levels underlies a number of neurodegenerative disorders. Defects in oxidative phosphorylation are associated with a number of neurodegenerative disorders. Mitochondria also play an important role in mediating the initiation of apoptosis.